Journal article

A semi-invariant V(alpha)10( ) T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

Adam P Uldrich, Onisha Patel, Garth Cameron, Daniel G Pellicci, E Bridie Day, Lucy C Sullivan, Konstantinos Kyparissoudis, Lars Kjer-Nielsen, Julian P Vivian, Benjamin Cao, Andrew G Brooks, Spencer J Williams, Petr Illarionov, Gurdyal S Besra, Stephen J Turner, Steven A Porcelli, James McCluskey, Mark J Smyth, Jamie Rossjohn, Dale I Godfrey

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2011


Awarded by US National Institutes of Health

Funding Acknowledgements

We thank M. Taniguchi (Chiba University Graduate School of Medicine) for J<INF>alpha</INF>18<SUP>-/-</SUP> mice; M. Kronenberg (La Jolla Institute for Allergy and Immunology) for the baculovirus-based CD1d expression system; P. Savage (Brigham Young University) for alpha-GalCer (C<INF>24:1</INF> PBS-44 analog); the Australian Synchrotron staff at the MX1 and MX2 beamlines of the Australian synchrotron for assistance with data collection; S. Mattarollo, S. Doak, S. Berzins and A. Denton for discussions and assistance with some experiments; K. Field, N. Sanders and M. Reitsma for assistance with flow cytometry; and M. Stirling and the staff of the Peter MacCallum Cancer Centre Animal House and D. Maksel from the Protein Crystallography Unit at Monash University for technical assistance. Supported by the Cancer Council of Victoria, the National Health and Medical Research Council of Australia (A. P. U., L. C. S., M. J. S. and D. I. G.), the Australian Research Council (D. I. G., O. P. and J. R.), the Cancer Research Institute (G. C.) and the US National Institutes of Health (AI45889 to S. A. P.).