Journal article
First complete genome sequence of infectious laryngotracheitis virus
SW Lee, PF Markham, JF Markham, I Petermann, AH Noormohammadi, GF Browning, NP Ficorilli, CA Hartley, JM Devlin
BMC Genomics | BIOMED CENTRAL LTD | Published : 2011
Open access
Abstract
Background: Infectious laryngotracheitis virus (ILTV) is an alphaherpesvirus that causes acute respiratory disease in chickens worldwide. To date, only one complete genomic sequence of ILTV has been reported. This sequence was generated by concatenating partial sequences from six different ILTV strains. Thus, the full genomic sequence of a single (individual) strain of ILTV has not been determined previously. This study aimed to use high throughput sequencing technology to determine the complete genomic sequence of a live attenuated vaccine strain of ILTV.Results: The complete genomic sequence of the Serva vaccine strain of ILTV was determined, annotated and compared to the concatenated ILTV..
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Funding Acknowledgements
The Rural Industries Research and Development Corporation, Australia, funded this study. JMD is supported by a fellowship from the Australian Research Council. NICTA is funded by the Australian Government as represented by the Department of Broadband, Communications and the Digital Economy and the Australian Research Council through the ICT Centre of Excellence program. The authors thank Kelly Ewen-White (Lifetech) for her expert advice and assistance.