Journal article

Major prospects for exploring canine vector borne diseases and novel intervention methods using 'omic technologies

Robin B Gasser, Cinzia Cantacessi, Bronwyn E Campbell, Andreas Hofmann, Domenico Otranto

PARASITES & VECTORS | BMC | Published : 2011

Abstract

Canine vector-borne diseases (CVBDs) are of major socioeconomic importance worldwide. Although many studies have provided insights into CVBDs, there has been limited exploration of fundamental molecular aspects of most pathogens, their vectors, pathogen-host relationships and disease and drug resistance using advanced, 'omic technologies. The aim of the present article is to take a prospective view of the impact that next-generation, 'omics technologies could have, with an emphasis on describing the principles of transcriptomic/genomic sequencing as well as bioinformatic technologies and their implications in both fundamental and applied areas of CVBD research. Tackling key biological questi..

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