Journal article

Dopamine-Mediated Continuous Assembly of Biodegradable Capsules

Christopher J Ochs, Tam Hong, Georgina K Such, Jiwei Cui, Almar Postma, Frank Caruso

CHEMISTRY OF MATERIALS | AMER CHEMICAL SOC | Published : 2011

Abstract

PGA-dopamine conjugates (PGA ) were synthesized and assembled onto silica particles to yield biodegradable capsules with tunable degradation properties. Increasing the dopamine content results in thicker films with a concomitant reduction in the degradation kinetics. These tailored capsules are expected to find application in diverse areas, including drug and gene delivery. © 2011 American Chemical Society. PDA