The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy
Kim A Connelly, Andrew Advani, Sandra Kim, Suzanne L Advani, Michael Zhang, Kathryn E White, Young M Kim, Colleen Parker, Kerri Thai, Henry Krum, Darren J Kelly, Richard E Gilbert
Journal of Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2011
Awarded by NHMRC
Sources of support: This work was supported by grants from the Canadian Institutes of Health Research (CIHR) and Novartis Pharma. K. A. C. was supported by a HSF Canada Phase 1 clinician scientist award, a TACTICS scholarship (Canada) and a NHMRC Neil Hamilton Fairley scholarship ID 440712. R. E. G. is a Canada Research Chair in Diabetes Complications and this work was supported, in part, thanks to the Canadian Diabetes Association and the Canada Research Chair Program. Dr A. A. is a Canadian Diabetes Association Clinician Scientist. Confocal microscopy was performed at the BioImaging Facility of St. Michael's Hospital, Toronto, Canada.Conflict of interest: K. A. C., H. K., R. E. G. and D.J.K. have received honoraria and research support from Novartis, the manufacturers of aliskiren.