Journal article

Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)

Nuh N Rahbari, O James Garden, Robert Padbury, Mark Brooke-Smith, Michael Crawford, Rene Adam, Moritz Koch, Masatoshi Makuuchi, Ronald P Dematteo, Christopher Christophi, Simon Banting, Val Usatoff, Masato Nagino, Guy Maddern, Thomas J Hugh, Jean-Nicolas Vauthey, Paul Greig, Myrddin Rees, Yukihiro Yokoyama, Sheung Tat Fan Show all

Surgery | MOSBY-ELSEVIER | Published : 2011

Abstract

BACKGROUND: Posthepatectomy liver failure is a feared complication after hepatic resection and a major cause of perioperative mortality. There is currently no standardized definition of posthepatectomy liver failure that allows valid comparison of results from different studies and institutions. The aim of the current article was to propose a definition and grading of severity of posthepatectomy liver failure. METHODS: A literature search on posthepatectomy liver failure after hepatic resection was conducted. Based on the normal course of biochemical liver function tests after hepatic resection, a simple and easily applicable definition of posthepatectomy liver failure was developed by the I..

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