Retinal Vascular Geometry Predicts Incident Retinopathy in Young People With Type 1 Diabetes A prospective cohort study from adolescence
Paul Benitez-Aguirre, Maria E Craig, Muhammad Bayu Sasongko, Alicia J Jenkins, Tien Yin Wong, Jie Jin Wang, Ning Cheung, Kim C Donaghue
Diabetes Care | AMER DIABETES ASSOC | Published : 2011
OBJECTIVE: To examine the association between retinal vascular geometry and subsequent development of incident retinopathy in young patients with type 1 diabetes. RESEARCH DESIGN AND METHODS: A prospective cohort study of 736 people with type 1 diabetes aged 12 to 20 years, retinopathy-free at baseline, attending an Australian tertiary care hospital. Retinopathy was determined from seven-field retinal photographs according to the modified Airlie House Classification. Retinal vascular geometry, including length/diameter ratio (LDR) and simple tortuosity (ST), was quantified in baseline retinal photographs. Generalized estimating equations were used to determine risk of retinopathy associated ..View full abstract
Awarded by National Health and Medical Research Council
Awarded by Juvenile Diabetes Research Foundation
The National Health and Medical Research Council (NHMRC 475605) and the Juvenile Diabetes Research Foundation (JDRF 5-2008-274) provided funds for this project.