Journal article

Retinal Vascular Geometry Predicts Incident Retinopathy in Young People With Type 1 Diabetes A prospective cohort study from adolescence

Paul Benitez-Aguirre, Maria E Craig, Muhammad Bayu Sasongko, Alicia J Jenkins, Tien Yin Wong, Jie Jin Wang, Ning Cheung, Kim C Donaghue

Diabetes Care | AMER DIABETES ASSOC | Published : 2011


OBJECTIVE: To examine the association between retinal vascular geometry and subsequent development of incident retinopathy in young patients with type 1 diabetes. RESEARCH DESIGN AND METHODS: A prospective cohort study of 736 people with type 1 diabetes aged 12 to 20 years, retinopathy-free at baseline, attending an Australian tertiary care hospital. Retinopathy was determined from seven-field retinal photographs according to the modified Airlie House Classification. Retinal vascular geometry, including length/diameter ratio (LDR) and simple tortuosity (ST), was quantified in baseline retinal photographs. Generalized estimating equations were used to determine risk of retinopathy associated ..

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Awarded by National Health and Medical Research Council

Awarded by Juvenile Diabetes Research Foundation

Funding Acknowledgements

The National Health and Medical Research Council (NHMRC 475605) and the Juvenile Diabetes Research Foundation (JDRF 5-2008-274) provided funds for this project.