A Genome-wide Comparison of the Functional Properties of Rare and Common Genetic Variants in Humans
Qianqian Zhu, Dongliang Ge, Jessica M Maia, Mingfu Zhu, Slave Petrovski, Samuel P Dickson, Erin L Heinzen, Kevin V Shianna, David B Goldstein
American Journal of Human Genetics | CELL PRESS | Published : 2011
Awarded by Bill and Melinda Gates Foundation
Awarded by National Institute of Allergy and Infectious Diseases Center for HIV/AIDS Vaccine Immunology
Awarded by National Institute of Neurological Disorders and Stroke
Awarded by National Institute of Mental Health
We thank K. Pelak, E. Ruzzo, A. Need, and T. Urban for helpful discussion and comments on the manuscript. We acknowledge J. Goedert, J. Milner, D. Valle, J. Hoover-Fong, N. Sobriera, J.P. McEvoy, A. Need, J. Silver, M. Silver, R. Radtke, N. Walley, A. Husain, D. Attix, L. Cirulli, J. McEvoy, K. Linney, W. Lowe, C. Depondt, G. Cavalleri, S. Sisodiya, and N. Delanty for supplying research material and C. Gumbs, H. Onabanjo, K. Cronin, and L. Little for DNA and RNA extraction. Funding for analysis of genomes was provided by Bill and Melinda Gates Foundation (grant 157412) with additional funding from National Institute of Allergy and Infectious Diseases Center for HIV/AIDS Vaccine Immunology grant AI067854, National Institute of Neurological Disorders and Stroke grant RC2NS070344, and National Institute of Mental Health grant RC2MH089915.