Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract
Mohamad Azhar, Pei-Yu Wang, Tony Frugier, Kyoko Koishi, Chuxia Deng, Peter G Noakes, Ian S McLennan
International Journal of Medical Sciences | IVYSPRING INT PUBL | Published : 2010
The skilled technical assistance of Mrs. Batchelor is gratefully acknowledged. Dr Edna C. Hardeman and Prof. Pierre Chambon are thanked for, respectively, gifting the alpha-skeletal actin promoter and Cre recombinase-ERT gene. This work was supported by the Marsden Fund Royal Society of New Zealand (I.S.M.), The Arizona Biomedical Research Commission (M.A.), The Steven M. Gootter Foundation (M.A.), The Stephen Michael Schneider Investigator Award for Pediatric Cardiovascular Research (M.A.), The William J. "Billy" Gieszl Endowment for Heart Research (M.A.), and R01 HL92508 (M.A.), and NHMRC Australia (PGN).