Journal article
Relationship between touch impairment and brain activation after lesions of subcortical and cortical somatosensory regions
LM Carey, DF Abbott, MR Harvey, A Puce, RJ Seitz, GA Donnan
Neurorehabilitation and Neural Repair | SAGE PUBLICATIONS INC | Published : 2011
Abstract
Background. The neural basis underlying somatosensory impairment and recovery poststroke is virtually unexplored. Objective. To investigate the relationship between touch discrimination impairment and task-related brain activation in stroke survivors with somatosensory impairment following subcortical or cortical lesions. Methods. A total of 19 stroke survivors with touch impairment were investigated using fMRI and a touch discrimination paradigm 1-month poststroke; 11 had subcortical and 8 cortical sensory lesions; 12 age-matched healthy controls were also studied. Mean task-related contrast images were regressed with sensory impairment using random effects analysis for each subgroup and th..
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Awarded by Australian Research Council
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research and/or authorship of this article: The authors received financial support for the research and authorship of this article from the National Health and Medical Research Council (NHMRC) of Australia [project grant number 307902; and Career Development Award number 307905 to LMC]; an Australian Research Council Future Fellowship [number FT0992299 to LMC]; the Austin Hospital Medical Research Foundation; the National Stroke Research Institute of Australia and by the Victorian Government's Operational Infrastructure Support Program. The funding sources had no role in conduct of the study or writing of the report.