Effect of vitamin D supplementation on muscle strength: A systematic review and meta-analysis

Abstract

Summary: This systematic review demonstrates that vitamin D supplementation does not have a significant effect on muscle strength in vitamin D replete adults. However, a limited number of studies demonstrate an increase in proximal muscle strength in adults with vitamin D deficiency. Introduction: The purpose of this study is to systematically review the evidence on the effect of vitamin D supplementation on muscle strength in adults. Methods: A comprehensive systematic database search was performed. Inclusion criteria included randomised controlled trials (RCTs) involving adult human participants. All forms and doses of vitamin D supplementation with or without calcium supplementation were ..