Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro
Cathryn L Haigh, Amelia R McGlade, Victoria Lewis, Colin L Masters, Victoria A Lawson, Steven J Collins
Free Radical Biology and Medicine | ELSEVIER SCIENCE INC | Published : 2011
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Awarded by NHMRC
The authors would like to acknowledge A/Prof AF Hill for the kind gift of the pIRES vector containing the PrP open reading frames and Dr Simon Drew for the SR-VAD-FMK reagent. The OBL-21 cell line used in this study were a kind gift of Dr Michael Oldstone, The Scripps Research Institute, La Jolla, California, USA. This study was funded by a Brain Foundation research grant. SJC is supported by an NH&MRC Practitioner Fellowship #400183 and an NH&MRC programme grant #400202. VL is supported by an NH&MRC Training (Postdoctoral) Fellowship #567123. VAL is supported by a University of Melbourne CR Roper fellowship.