Disproportionate Exercise Load and Remodeling of the Athlete's Right Ventricle
Andre La Gerche, Hein Heidbuechel, Andrew T Burns, Don J Mooney, Andrew J Taylor, Heinz B Pfluger, Warrick J Inder, Andrew I Macisaac, David L Prior
Medicine and Science in Sports and Exercise | LIPPINCOTT WILLIAMS & WILKINS | Published : 2011
PURPOSE: There is evolving evidence that intense exercise may place a disproportionate load on the right ventricle (RV) when compared with the left ventricle (LV) of the heart. Using a novel method of estimating end-systolic wall stress (ES-σ), we compared the RV and LV during exercise and assessed whether this influenced chronic ventricular remodeling in athletes. METHODS: For this study, 39 endurance athletes (EA) and 14 nonathletes (NA) underwent resting cardiac magnetic resonance (CMR), maximal oxygen uptake (VO2), and exercise echocardiography studies. LV and RV end-systolic wall stress (ES-σ) were calculated using the Laplace relation (ES-σ = Pr/(2h)). Ventricular size and wall thickne..View full abstract
This project was financed, in part, by a Cardiovascular Lipid Grant (Pfizer, Australia). A. L. G. is supported by a postgraduate scholarship (National Health and Medical Research Council/National Heart Foundation, Australia). A. J. T. is supported by a National Health and Medical Research Council Program Grant, Australia.