Journal article

In Vitro and In Vivo Anthelmintic Activity of Terminalia arjuna Bark

Hafiz Allah Bachaya, Zafar Iqbal, Muhammad Nisar Khan, Abdul Jabbar, Anwarul Hassan Gilani, undefined Islam-Ud-Din

International Journal of Agriculture and Biology | FRIENDS SCIENCE PUBL | Published : 2009

Abstract

The present study was carried out to evaluate the anthelmintic activity of Terminalia arjuna (Roxb.) bark locally used as an anthelmintic. Lethal median concentration (LC50 values) of methanolic extract of T. arjuna bark in egg hatch and larval development tests against Haemonchus contortus ova and larva were found to be 645.65 and 467.74 μg mL-1, respectively. In adult motility assay, efficacy of the extract was evident by the mortality of H. contortus at different hours post exposure. In vivo results revealed maximum (87.3%) egg count percent reduction (ECR) in sheep treated with crude methanolic extract @ 3 g kg-1 body weight on day 11 post-treatment (PT). The data revealed dose-dependent..

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University of Melbourne Researchers