Journal article
Familial recurrence risks for multiple sclerosis in Australia
C O'Gorman, S Freeman, BV Taylor, H Butzkueven, SA Broadley, M Bahlo, DR Booth, MA Brown, SJ Foote, LR Griffiths, TJ Kilpatrick, J Lechner-Scott, P Moscato, VM Perreau, RJ Scott, J Stankovich, GJ Stewart, C Chapman, M Marriot, M Tanner Show all
Journal of Neurology Neurosurgery and Psychiatry | BMJ PUBLISHING GROUP | Published : 2011
Abstract
Background: Genetic susceptibility to multiple sclerosis (MS) has been recognised for many years. Considerable data exist from the northern hemisphere regarding the familial recurrence risks for MS, but there are few data for the southern hemisphere and regions at lower latitude such as Australia. To investigate the interaction between environmental and genetic causative factors in MS, the authors undertook a familial recurrence risk study in three latitudinally distinct regions of Australia. Methods: Immediate and extended family pedigrees have been collected for three cohorts of people with MS in Queensland, Victoria and Tasmania spanning 158 of latitude. Age of onset data from Queensland ..
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