Journal article
The relationship between complex fractionated electrograms and atrial low-voltage zones during atrial fibrillation and paced rhythm
AW Teh, PM Kistler, G Lee, C Medi, PM Heck, SJ Spence, PB Sparks, JB Morton, P Sanders, JM Kalman
Europace | Published : 2011
Abstract
AimsMapping of atrial fibrillation (AF) involves identification of low-voltage regions associated with complex fractionated electrograms (CFE) which theoretically represent abnormal substrate and targets for ablation. Whether low-voltage CFE areas also identify abnormal substrate during paced rhythm is unknown. Methods and resultsTwelve patients with persistent AF undergoing ablation of AF had high-density three-dimensional electroanatomic maps created during AF and paced rhythm (24 maps) and the mean voltage during AF and paced rhythm was compared for eight segments of the left atrium (LA). The following were correlated during AF and paced rhythm: regional mean voltage; low voltage (defined..
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Funding Acknowledgements
Drs Teh and Medi are the recipients of a postgraduate research scholarship from the National Heart Foundation of Australia. Dr Lee is the recipient of a postgraduate research scholarship from the National Health and Medical Research Council. Drs Teh, Medi and Lee are the recipients of a cardiovascular and lipid research grant from Pfizer. Dr Kistler is supported by a Research Investigatorship from the Cardiac Society of Australia and New Zealand. Dr Sanders reports having served on the advisory board of and having received lecture fees and research funding from St Jude Medical, Bard Electrophysiology, Biosense-Webster, and Medtronic.