Journal article

Identification of tammar wallaby SIRH12, derived from a marsupial-specific retrotransposition event

R Ono, Y Kuroki, M Naruse, M Ishii, S Iwasaki, A Toyoda, A Fujiyama, G Shaw, MB Renfree, T Kaneko-Ishino, F Ishino

DNA Research | OXFORD UNIV PRESS | Published : 2011

Open access

Abstract

In humans and mice, there are 11 genes derived from sushi-ichi related retrotransposons, some of which are known to play essential roles in placental development. Interestingly, this family of retrotransposons was thought to exist only in eutherian mammals, indicating their significant contributions to the eutherian evolution, but at least one, PEG10, is conserved between marsupials and eutherians. Here we report a novel sushi-ichi retrotransposon-derived gene, SIRH12, in the tammar wallaby, an Australian marsupial species of the kangaroo family. SIRH12 encodes a protein highly homologous to the sushi-ichi retrotransposon Gag protein in the tammar wallaby, while SIRH12 in the South American ..

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University of Melbourne Researchers

Grants

Awarded by Japan Society for the Promotion of Science


Funding Acknowledgements

This work was supported in part by Grants-in-Aid for Scientific Research on Priority Area (R.O.) and Innovative Areas 'Genome Science' (R.O., Y.K., A.T) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan, Grant-in-Aid for Young Scientist (R.O.), Creative Science Research (F.I. and T.K.-I.), and Bilateral Program on Joint Research Project (F.I.) from the Japan Society for the Promotion of Science (J.S.P.S.), grants from Mochida Memorial Foundation for Medical and Pharmaceutical Research and The Nakajima Foundation (R.O.). M.B.R. was supported by an Australian Research Council Federation Fellowship, and G.S. and M.B.R. by the ARC Centre of Excellence in Kangaroo Genomics.