Journal article

Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice

Michael Kraft, Ion Cristian Cirstea, Anne Kathrin Voss, Tim Thomas, Ina Goehring, Bilal N Sheikh, Lavinia Gordon, Hamish Scott, Gordon K Smyth, Mohammad Reza Ahmadian, Udo Trautmann, Martin Zenker, Marco Tartaglia, Arif Ekici, Andre Reis, Helmuth-Guenther Doerr, Anita Rauch, Christian Thomas Thiel

Journal of Clinical Investigation | AMER SOC CLINICAL INVESTIGATION INC | Published : 2011


Awarded by BMBF network

Awarded by DFG

Awarded by German Ministry of Science and Education [BMBF]

Funding Acknowledgements

We thank the family for giving their consent for this study. This study was supported by the IZKF grant ES to A. Rauch, the BMBF network grant SKELNET (GFGM01141901) to A. Rauch and A. Reis, the DFG grant ZE524/4-1 to M. Zenker, the DFG grant TH896/3-1 to C.T. Thiel, and grants from the F.R.S.-FNRS and the Australian NHMRC. This work was performed as part of our research study addressing the genetics of mental retardation, which was approved by the research ethics committee of the Medical Faculty of the University of Erlangen-Nuremberg. M.R. Ahmadian was supported by the NGFNplus-program of the German Ministry of Science and Education [BMBF, grant 01GS08100] and the Research Committee of the Medical Faculty of the Heinrich-Heine University Dusseldorf.