Journal article

Structural Basis of Bcl-x(L) Recognition by a BH3-Mimetic alpha/beta-Peptide Generated by Sequence-Based Design

Erinna F Lee, Brian J Smith, W Seth Horne, Kelsey N Mayer, Marco Evangelista, Peter M Colman, Samuel H Gellman, W Douglas Fairlie

ChemBioChem | WILEY-BLACKWELL | Published : 2011

University of Melbourne Researchers

Grants

Awarded by Australian Research Council


Awarded by NHMRC of Australia


Awarded by Leukemia and Lymphoma Society


Awarded by US NIH


Awarded by NHMRC IRIISS


Awarded by NATIONAL CANCER INSTITUTE


Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES


Funding Acknowledgements

This work was supported by fellowships and grants from Australian Research Council (Discovery Project Grant DP1093909 to W.D.F., P.M.C., B.J.S.), the NHMRC of Australia (Program Grant 461221 to P.M.C.), Australian Cancer Research Foundation (P.M.C.), the Leukemia and Lymphoma Society (SCOR 7015-02), and the Leukaemia Foundation of Australia (Phillip Desbrow Postdoctoral Fellowship to E.F.L.). In addition, this research was supported by US NIH grant GM-56414 (to S.H.G). W.S.H. was supported in part by a fellowship from the US NIH (CA119875). Crystallization trials were performed at the Bio21 Collaborative Crystallisation Centre. Data were collected on the MX2 beamline at the Australian Synchrotron, Victoria, Australia. Infrastructure support from NHMRC IRIISS grant 361646 and the Victorian State Government OIS grant is gratefully acknowledged.