Journal article

Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes

Luis G Carvajal-Carmona, Jean-Baptiste Cazier, Angela M Jones, Kimberley Howarth, Peter Broderick, Alan Pittman, Sara Dobbins, Albert Tenesa, Susan Farrington, James Prendergast, Evi Theodoratou, Rebecca Barnetson, David Conti, Polly Newcomb, John L Hopper, Mark A Jenkins, Steven Gallinger, David J Duggan, Harry Campbell, David Kerr Show all

Human Molecular Genetics | OXFORD UNIV PRESS | Published : 2011

Grants

Awarded by Wellcome Trust Centre for Human Genetics, Oxford


Awarded by Medical Research Council


Awarded by Scottish Executive Chief Scientist's Office


Awarded by National Institutes of Health


Awarded by Australian Colorectal Cancer Family Registry


Awarded by USC Familial Colorectal Neoplasia Collaborative Group


Awarded by Mayo Clinic Cooperative Family Registry for Colon Cancer Studies


Awarded by Ontario Registry for Studies of Familial Colorectal Cancer


Awarded by Seattle Colorectal Cancer Family Registry


Awarded by University of Hawaii Colorectal Cancer Family Registry


Awarded by Cancer Research UK


Awarded by Chief Scientist Office


Funding Acknowledgements

Cancer Research UK provided principal funding for this study. The Oxford Comprehensive Biomedical Research Centre (I.T.) and the EU FP7 CHIBCHA grant (to L.G.C.-C. and I.T.) also provided funding. Core infrastructure support to the Wellcome Trust Centre for Human Genetics, Oxford, was provided by grant 075491/Z/04. The Medical Research Council (G0000657-53203), CORE and Scottish Executive Chief Scientist's Office (K/OPR/2/2/D333, CZB/4/449) provided additional funding (to M.D.). The Colon Cancer Family Registry was supported by the National Cancer Institute and National Institutes of Health under Request for Application #CA-95-011, and through cooperative agreements with the Australian Colorectal Cancer Family Registry (UO1 CA097735), the USC Familial Colorectal Neoplasia Collaborative Group (UO1 CA074799), Mayo Clinic Cooperative Family Registry for Colon Cancer Studies (UO1 CA074800), Ontario Registry for Studies of Familial Colorectal Cancer (UO1 CA074783), Seattle Colorectal Cancer Family Registry (UO1 CA074794) and The University of Hawaii Colorectal Cancer Family Registry (UO1 CA074806).