A Re-Examination of Wolbachia-Induced Cytoplasmic Incompatibility in California Drosophila simulans
Lauren B Carrington, Jeremy R Lipkowitz, Ary A Hoffmann, Michael Turelli
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2011
BACKGROUND: In California Drosophila simulans, the maternally inherited Riverside strain Wolbachia infection (wRi) provides a paradigm for rapid spread of Wolbachia in nature and rapid evolutionary change. wRi induces cytoplasmic incompatibility (CI), where crosses between infected males and uninfected females produce reduced egg-hatch. The three parameters governing wRi infection-frequency dynamics quantify: the fidelity of maternal transmission, the level of cytoplasmic incompatibility, and the relative fecundity of infected females. We last estimated these parameters in nature in 1993. Here we provide new estimates, under both field and laboratory conditions. Five years ago, we found that..View full abstract
Awarded by National Science Foundation
This research was supported by grants from the Foundation for the National Institutes of Health, through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation (MT), the National Science Foundation (DEB 0815145 to MT) and a Laureate Fellowship from the Australian Research Council (AAH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.