Genome-wide association studies for feedlot and growth traits in cattle
S Bolormaa, BJ Hayes, K Savin, R Hawken, W Barendse, PF Arthur, RM Herd, ME Goddard
JOURNAL OF ANIMAL SCIENCE | AMER SOC ANIMAL SCIENCE | Published : 2011
A genome wide-association study for production traits in cattle was carried out using genotype data from the 10K Affymetrix (Santa Clara, CA) and the 50K Illumina (San Diego, CA) SNP chips. The results for residual feed intake (RFI), BW, and hip height in 3 beef breed types (Bos indicus, Bos taurus, and B. indicus × B. taurus), and for stature in dairy cattle, are presented. The aims were to discover SNP associated with all traits studied, but especially RFI, and further to test the consistency of SNP effects across different cattle populations and breed types. The data were analyzed within data sets and within breed types by using a mixed model and fitting 1 SNP at a time. In each case, the..View full abstract
We acknowledge funding from Cooperative Research Centre for Beef Genetic Technologies (Armidale, New South Wales, Australia) for this study. We are thankful to Toni Reverter (CSIRO Livestock Industries, Queensland, Australia) for advice regarding which individuals to genotype and for providing a pedigree file. In addition, we thank David Johnston [Animal Genetics and Breeding Unit (AGBU), New South Wales, Australia] for his advice and comments and Yuandan Zhang (AGBU) and Bruce Tier (AGBU) for cleaning the genotype files.