Journal article
Preclinical evaluation of caprylic acid-fractionated igg antivenom for the treatment of taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea
M Vargas, A Segura, M Herrera, M Villalta, R Estrada, M Cerdas, O Paiva, T Matainaho, SD Jensen, KD Winkel, G León, JM Gutiérrez, DJ Williams
Plos Neglected Tropical Diseases | Published : 2011
Abstract
Background: Snake bite is a common medical emergency in Papua New Guinea (PNG). The taipan, Oxyuranus scutellatus, inflicts a large number of bites that, in the absence of antivenom therapy, result in high mortality. Parenteral administration of antivenoms manufactured in Australia is the current treatment of choice for these envenomings. However, the price of these products is high and has increased over the last 25 years; consequently the country can no longer afford all the antivenom it needs. This situation prompted an international collaborative project aimed at generating a new, low-cost antivenom against O. scutellatus for PNG. Methodology/Principal Findings: A new monospecific equine..
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Grants
Awarded by Vicerrectoria de Investigacion, Universidad de Costa Rica
Funding Acknowledgements
This study was supported by Vicerrectoria de Investigacion, Universidad de Costa Rica (project 741-A9-003); the PNG Office of Higher Education, CTP Limited (Milne Bay Estates), and the Australian Venom Research Unit (University of Melbourne), which is funded by the Australian Government Department of Health and Ageing, the Australia Pacific Science Foundation and Snowy Nominees. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.