Journal article

Reproductive factors associated with mammographic density: a Korean co-twin control study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee, Donghun Lee



To determine the mechanism by which menstrual and reproductive factors are associated with the risk of breast cancer, we examined the relationships between mammographic density and known menstrual and reproductive risk factors for breast cancer. A co-twin control study was conducted with 122 pairs of monozygotic Korean female twins selected from the Healthy Twin study. Mammographic density was measured from digital mammograms using a computer-assisted method. Information on selected menstrual and reproductive factors was collected through a self-administered questionnaire. Within-pair differences for each mammographic measure were regressed against within-pair differences for each menstrual ..

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Awarded by National Institute of Health

Awarded by Korean Ministry of Education, Science and Technology

Awarded by Samsung Biomedical Research Institute

Funding Acknowledgements

This study was supported by the National Genome Research Institute, Korea, National Institute of Health research contract (budgets 2005-347-2400-2440-215, 2006-347-2400-2440-215, 2007-347-2400-2440-215, 2008-E00255-00, and 2009-E00500-00), Korean Ministry of Education, Science and Technology (Grant Number M10305030005), and the Samsung Biomedical Research Institute (#SBRI C-A9-218-1). The views expressed in this paper are those of the authors and not necessarily any funding body.