Optic Disc Evaluation in Optic Neuropathies The Optic Disc Assessment Project
Evelyn C O'Neill, Helen V Danesh-Meyer, George XY Kong, Alex W Hewitt, Michael A Coote, David A Mackey, Jonathan G Crowston
Ophthalmology | ELSEVIER SCIENCE INC | Published : 2011
OBJECTIVE: Optic nerve morphology is affected by genetic and acquired disease. Glaucoma is the most common optic neuropathy; autosomal-dominant optic atrophy (ADOA) and Leber's hereditary optic neuropathy (LHON) are the most prevalent hereditary optic neuropathies. These 3 entities can exhibit similar topographical changes at the optic nerve head. Both ADOA and LHON have been reported to be misdiagnosed as glaucoma. Our aim was to determine whether glaucoma subspecialists and neuro-ophthalmologists can distinguish these diagnoses on optic disc assessment alone. DESIGN: Observational study. PARTICIPANTS: Twenty-three optic nerve experts. METHODS: We randomized and masked 60 high-resolution st..View full abstract
Supported by the Cranbourne Trust and Helen McPherson Trust Grant; CERA receives Operational Infrastructure Support from the Victorian Government.