Journal article
Distribution of tidal ventilation during volume-targeted ventilation is variable and influenced by age in the preterm lung
RK Armstrong, HR Carlisle, PG Davis, A Schibler, DG Tingay
Intensive Care Medicine | SPRINGER | Published : 2011
Abstract
Synchronised volume-targeted ventilation (SIPPV + VTV) attempts to reduce lung injury by standardising volume delivery to the preterm lung. The aim of this study is to describe the regional distribution and variability of ventilation within the preterm lung during SIPPV + VTV. Twenty-seven stable, supine, preterm infants with <32 weeks gestation receiving SIPPV + VTV were studied. From each infant, the anterior-to-posterior impedance change due to tidal ventilation (δZ VT; countless units) was determined during every breath from three, 30-s, electrical impedance tomography recordings. δZ VT within the anterior, middle and posterior thirds of the chest were compared using area under the curve..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The authors wish to thank Brenda Argus and Stephanie Tan-Kristanto for their assistance with this study. D.G.T. is supported by a National Health and Medical Research Council Clinical Research Fellowship (Grant ID 491286).