Skeletal morbidity among survivors of critical illness

Abstract

OBJECTIVES: To describe the incident fracture rate in survivors of critical illness and to compare fracture risk with population-matched control subjects. DESIGN: Retrospective longitudinal case-cohort study. SETTING: A tertiary adult intensive care unit in Australia. PATIENTS: All patients ventilated admitted to intensive care and requiring mechanical ventilation for ≥48 hrs between January 1998 and December 2005. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: New fractures were identified in the study population for the postintensive care unit period (intensive care unit discharge to January 2008). The incident fracture rate and age-adjusted fracture risk of the female intensive care ..