Journal article

Ascaris suum draft genome

Aaron R Jex, Shiping Liu, Bo Li, Neil D Young, Ross S Hall, Yingrui Li, Linfeng Yang, Na Zeng, Xun Xu, Zijun Xiong, Fangyuan Chen, Xuan Wu, Guojie Zhang, Xiaodong Fang, Yi Kang, Garry A Anderson, Todd W Harris, Bronwyn E Campbell, Johnny Vlaminck, Tao Wang Show all

Nature | NATURE PUBLISHING GROUP | Published : 2011

Abstract

Parasitic diseases have a devastating, long-term impact on human health, welfare and food production worldwide. More than two billion people are infected with geohelminths, including the roundworms Ascaris (common roundworm), Necator and Ancylostoma (hookworms), and Trichuris (whipworm), mainly in developing or impoverished nations of Asia, Africa and Latin America. In humans, the diseases caused by these parasites result in about 135,000 deaths annually, with a global burden comparable with that of malaria or tuberculosis in disability-adjusted life years. Ascaris alone infects around 1.2 billion people and, in children, causes nutritional deficiency, impaired physical and cognitive develop..

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Grants

Awarded by Victorian Life Sciences Computation Initiative on its Peak Computing Facility at the University of Melbourne


Funding Acknowledgements

This project was funded by the Australian Research Council. This research was supported by a Victorian Life Sciences Computation Initiative (grant number VR0007) on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government. Other support from the Australian Academy of Science, the Australian-American Fulbright Commission, Melbourne Water Corporation, and the IBM Research Collaboratory for Life Sciences-Melbourne is gratefully acknowledged. P. W. S. is an investigator with the Howard Hughes Medical Institute. A.R.J. held a CDA1 (Industry) from the National Health and Medical Research Council of Australia. We are indebted to the faculty and staff of the BGI-Shenzhen, who contributed to this study. We also acknowledge the contributions of staff at WormBase (www.wormbase.org).