Journal article

A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma

Mark C Fitzgerald, Julie Y Chan, Andrew W Ross, Susan M Liew, Warwick W Butt, David Baguley, Hatem H Salem, Matthias K Russ, Conor Deasy, Katherine E Martin, Joseph K Mathew, Jeffrey V Rosenfeld

Medical Journal of Australia | AUSTRALASIAN MED PUBL CO LTD | Published : 2011

Abstract

We report a case of compassionate use of a haemoglobin-based oxygen carrier in a severely injured Jehovah's Witness patient, for whom survival was considered unlikely. Severe anaemia and cardiac hypoxia were reversed after slow infusion of this agent. No vasoactive side effects were associated with the treatment, possibly due to the slow infusion, and the patient survived.