Birthweight and mortality in adulthood: a systematic review and meta-analysis
Kari R Risnes, Lars J Vatten, Jennifer L Baker, Karen Jameson, Ulla Sovio, Eero Kajantie, Merete Osler, Ruth Morley, Markus Jokela, Rebecca C Painter, Valter Sundh, Geir W Jacobsen, Johan G Eriksson, Thorkild IA Sorensen, Michael B Bracken
International Journal of Epidemiology | OXFORD UNIV PRESS | Published : 2011
BACKGROUND: Small birth size may be associated with increased risk of cardiovascular diseases (CVD), whereas large birth size may predict increased risk of obesity and some cancers. The net effect of birth size on long-term mortality has only been assessed in individual studies, with conflicting results. METHODS: The Meta-analyses of Observational Studies in Epidemiology (MOOSE) guidelines for conducting and reporting meta-analysis of observational studies were followed. We retrieved 22 studies that assessed the association between birthweight and adult mortality from all causes, CVD or cancer. The studies were systematically reviewed and those reporting hazard ratios (HRs) and 95% confidenc..View full abstract
Liaison Committee between the Central Norway Regional Health Authority (RHA); Norwegian University of Science and Technology (NTNU to K.R.R.).