The age-related risk of co-existing meningitis in children with urinary tract infection

M Tebruegge; A Pantazidou; V Clifford; G Gonis; N Ritz; T Connell; N Curtis

Journal article

The age-related risk of co-existing meningitis in children with urinary tract infection

M Tebruegge, A Pantazidou, V Clifford, G Gonis, N Ritz, T Connell, N Curtis

Plos One | Published : 2011

DOI: 10.1371/journal.pone.0026576

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Abstract

Objective: The primary aim of this study was to determine age-stratified rates of co-existing bacterial meningitis in children with urinary tract infection (UTI). The secondary aims of this study were to determine the causative pathogens of UTI, and the clinical features and outcome of children with co-existing meningitis. Methods: Analysis of data collected over a nine-year period at a tertiary pediatric hospital in Australia. Study population: children below 16 years of age with culture-confirmed UTI and a paired CSF sample. Results: A total of 748 episodes in 735 cases were included in the final analysis. The commonest pathogens causing UTI were Escherichia coli (67.4%), Enterococcus faec..

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University of Melbourne Researchers

Vanessa Clifford Author

Nigel Curtis Author

Grants

Funding Acknowledgements

No external funding was received for this study. MT and NR were supported by Fellowship awards from the European Society for Paediatric Infectious Diseases and International Research Scholarships provided by the University of Melbourne. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.