Journal article

The role of parent-initiated oral corticosteroids in preschool wheeze and school-aged asthma

Peter J Vuillermin, Colin F Robertson, Mike South

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2011

Abstract

PURPOSE OF REVIEW: To review the theoretical background and current evidence regarding parent-initiated oral corticosteroid (PIOCS) therapy in preschool wheeze and asthma in school-aged children. RECENT FINDINGS: In school-aged children with asthma PIOCS, given during acute episodes, has been associated with a modest reduction in asthma symptoms and health resource utilisation. In preschool wheeze, OCS (including PIOCS) therapy appears to be ineffective. SUMMARY: PIOCS is associated with modest benefits among school-aged children with acute asthma but is not effective among children with preschool wheeze. In older children with asthma, the potential benefits of PIOCS must be balanced against..

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