The role of parent-initiated oral corticosteroids in preschool wheeze and school-aged asthma
Peter J Vuillermin, Colin F Robertson, Mike South
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2011
PURPOSE OF REVIEW: To review the theoretical background and current evidence regarding parent-initiated oral corticosteroid (PIOCS) therapy in preschool wheeze and asthma in school-aged children. RECENT FINDINGS: In school-aged children with asthma PIOCS, given during acute episodes, has been associated with a modest reduction in asthma symptoms and health resource utilisation. In preschool wheeze, OCS (including PIOCS) therapy appears to be ineffective. SUMMARY: PIOCS is associated with modest benefits among school-aged children with acute asthma but is not effective among children with preschool wheeze. In older children with asthma, the potential benefits of PIOCS must be balanced against..View full abstract
P.J.V. is funded by the National Health and Medical Research Council of Australia. There are no conflicts of interest.