Journal article
Impact of persistent antiphospholipid antibodies on risk of incident symptomatic thromboembolism in children: A systematic review and meta-analysis
G Kenet, S Aronis, Y Berkun, M Bonduel, A Chan, NA Goldenberg, S Holzhauer, A Iorio, J Journeycake, R Junker, C Male, M Manco-Johnson, P Massicotte, R Mesters, P Monagle, H Van Ommen, L Rafini, P Simioni, G Young, U Nowak-Göttl
Seminars in Thrombosis and Hemostasis | Published : 2011
Abstract
The aim of this study was to estimate the impact of antiphospholipid (aPL) antibodies on the risk of incident thromboembolism (TE; arterial and venous) in children via meta-analysis of published observational studies. A systematic search of electronic databases (Medline, EMBASE, OVID, Web of Science, The Cochrane Library) for studies published from 1966 to 2010 was conducted using keywords in combination both as MeSH terms and text words. Two authors independently screened citations and those meeting the a priori defined inclusion criteria were retained. Data on year of publication, study design, country of origin, number of patients/controls, ethnicity, TE type, and frequency of recurrence ..
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Funding Acknowledgements
The study was supported by grants from the "Forderverein Schlaganfall und Thrombosen im Kindesalter e.V." The study supporters had no role in study design, data collection, data analysis, data interpretation, or in writing of the report.