Journal article

Dynamic lactate indices as predictors of outcome in critically ill patients

Alistair Nichol, Michael Bailey, Moritoki Egi, Ville Pettila, Craig French, Edward Stachowski, Michael C Reade, David James Cooper, Rinaldo Bellomo

CRITICAL CARE | BMC | Published : 2011


INTRODUCTION: Dynamic changes in lactate concentrations in the critically ill may predict patient outcome more accurately than static indices. We aimed to compare the predictive value of dynamic indices of lactatemia in the first 24 hours of intensive care unit (ICU) admission with the value of more commonly used static indices. METHODS: This was a retrospective observational study of a prospectively obtained intensive care database of 5,041 consecutive critically ill patients from four Australian university hospitals. We assessed the relationship between dynamic lactate values collected in the first 24 hours of ICU admission and both ICU and hospital mortality. RESULTS: We obtained 36,673 l..

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