Journal article

Bicarbonate in diabetic ketoacidosis - a systematic review

Horng Ruey Chua, Antoine Schneider, Rinaldo Bellomo

ANNALS OF INTENSIVE CARE | SPRINGER HEIDELBERG | Published : 2011

Abstract

OBJECTIVE: This study was designed to examine the efficacy and risk of bicarbonate administration in the emergent treatment of severe acidemia in diabetic ketoacidosis (DKA). METHODS: PUBMED database was used to identify potentially relevant articles in the pediatric and adult DKA populations. DKA intervention studies on bicarbonate administration versus no bicarbonate in the emergent therapy, acid-base studies, studies on risk association with cerebral edema, and related case reports, were selected for review. Two reviewers independently conducted data extraction and assessed the citation relevance for inclusion. RESULTS: From 508 potentially relevant articles, 44 were included in the syste..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

Dr Horng Ruey Chua was a recipient of the Singapore Health Manpower Development Programme (HMDP) award in 2010, which was co-funded by the Ministry of Health (MOH) Singapore, and National University Health System (NUHS) Singapore. The funds were utilized for his clinical and research training in Austin Health, Melbourne, Australia.