Reducing the exome search space for Mendelian diseases using genetic linkage analysis of exome genotypes
Katherine R Smith, Catherine J Bromhead, Michael S Hildebrand, A Eliot Shearer, Paul J Lockhart, Hossein Najmabadi, Richard J Leventer, George McGillivray, David J Amor, Richard J Smith, Melanie Bahlo
Genome Biology | BIOMED CENTRAL LTD | Published : 2011
Awarded by NHMRC
Awarded by NIH-NIDCD
Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
We acknowledge Kate Pope, Hayley Mountford and Elizabeth Fitzpatrick (Accelerated Gene Identification Project, Murdoch Childrens Research Institute) for assistance with families A, T and M. This work was supported by an Australian Research Council (ARC) Future Fellowship (MB), an NHMRC Program Grant (MB, DJA), NIH-NIDCD grant RO1 DCOO2842 (RJHS), NHMRC overseas biomedical postdoctoral training fellowship 546943 (MSH), a Doris Duke Fellowship (AES) and the Victorian Government's Operational Infrastructure Support Program (PL, RJL, GM, DJA). Funding sources had no role any of the following: design of the study; the collection, analysis, and interpretation of data; the writing of the manuscript; and the decision to submit the manuscript for publication.