Effects of non-synchronised nasal intermittent positive pressure ventilation on spontaneous breathing in preterm infants

Abstract

Background: Nasal intermittent positive pressure ventilation (NIPPV) may be beneficial but the mechanisms of action are undetermined. Aim: To investigate the effects of non-synchronised NIPPV on spontaneous breathing in premature infants. Methods: 10 infants receiving ventilator generated nonsynchronised NIPPV were studied for 30 min. Delivered pressure was measured at the nose; respiration was recorded using respiratory inductance plethysmography. Oxygen saturation, carbon dioxide, heart rate, inspired oxygen and video images were recorded. Results: Median gestational age, birth weight, age and study weight were 25 +3 weeks, 797 g, 24 days and 1076 g. When the NIPPV pressure peak commenced ..