Journal article

Electroanatomic properties of the pulmonary veins: Slowed conduction, low voltage and altered refractoriness in AF patients

AW Teh, PM Kistler, G Lee, C Medi, PM Heck, S Spence, JB Morton, P Sanders, JM Kalman

Journal of Cardiovascular Electrophysiology | WILEY | Published : 2011

Abstract

Electroanatomic Properties of the Pulmonary Veins. Introduction: Rapid PV activity is critical in initiating and maintaining AF. The underlying substrate responsible for this remains uncertain. We sought to identify if patients with paroxysmal (PAF) and persistent atrial fibrillation (PeAF) have an abnormal substrate within the pulmonary veins (PVs). Methods and Results: Thirty-nine patients with AF (21 PAF, 18 PeAF) were compared with 15 age-matched controls with left-sided accessory pathways (AVRT). High-density 3D electroanatomic maps of the PVs were created. PV voltage, conduction, PV muscle sleeve length, effective refractory periods (ERPs) of the PVs, posterior left atrium (PLA), left ..

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Grants

Funding Acknowledgements

Drs. Teh and Medi are the recipients of a postgraduate research scholarship from the National Heart Foundation of Australia. Dr. Lee is the recipient of a postgraduate research scholarship from the Cardiac Society of Australia and New Zealand. Drs. Teh, Medi, and Lee are the recipients of a cardiovascular and lipid research grant from Pfizer. Dr. Kistler is supported by a Research Investigatorship from the Cardiac Society of Australia and New Zealand.Dr. Sanders reports having served on the advisory board of and having received lecture fees and research funding from St. Jude Medical, Bard Electrophysiology, Biosense-Webster, and Medtronic.