Journal article

alpha,beta-Unsaturated monoterpene acid glucose esters: Structural diversity, bioactivities and functional roles

Jason QD Goodger, Ian E Woodrow



The glycosylation of lipophilic small molecules produces many important plant secondary metabolites. The majority of these are O-glycosides with relatively fewer occurring as glucose esters of aromatic or aliphatic acids. In particular, monoterpene acid glucose esters have much lower structural diversity and distribution compared to monoterpene glycosides. Nevertheless, there have been over 20 monoterpene acid glucose esters described from trees in the genus Eucalyptus (Myrtaceae) in recent years, all based on oleuropeic acid, menthiafolic acid or both. Here we review all of the glucose esters containing these monoterpenoids identified in plants to date. Many of the compounds contain phenoli..

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Awarded by Australian Research Council

Funding Acknowledgements

J.Q.D.G. and I.E.W. were supported by a grant from the Australian Research Council (Project DP1094530). We thank Prof. M.A. Rizzacasa and Dr. S.J. Williams, School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne for advice. We also thank Prof. B.L. Moller, VKR Research Centre Pro-Active Plants, Copenhagen, Denmark for helpful discussions and sharing our enthusiasm towards this group of compounds.