The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry
Stella Hughes, Timothy Spelman, Maria Trojano, Alessandra Lugaresi, Guillermo Izquierdo, Francois Grand'Maison, Pierre Duquette, Marc Girard, Pierre Grammond, Celia Oreja-Guevara, Raymond Hupperts, Cavit Boz, Roberto Bergamaschi, Giorgio Giuliani, Maria Edite Rio, Jeannette Lechner-Scott, Vincent van Pesch, Gerardo Iuliano, Marcela Fiol, Freek Verheul Show all
Journal of Neurology, Neurosurgery and Psychiatry | BMJ PUBLISHING GROUP | Published : 2012
Awarded by Economic and Social Research Council
This study was funded by the MSBase Foundation, a not-for-profit organisation. The MSBase Foundation receives financial support from Merck Serono, Biogen Idec, Novartis Pharma, Bayer Schering and Sanofi Aventis.SHu has received unrestricted educational grants from Bayer Schering Australia, Biogen Idec, Merck Serono and Sanofi Aventis. MT received honoraria for consultancy and/or speaking from Biogen Idec, Sanofi-Aventis, Merck Serono and Bayer Schering and research grants from Merck Serono, Biogen Idec and Novartis Pharma. AL is a Biogen Dompe, Merck Serono and Bayer Schering advisory board member. She receives travel grants and honoraria from Bayer Schering, Biogen Dompe, Merck Serono, Novartis, Sanofi Aventis and Teva and research grants from Bayer Schering, Biogen Dompe, Merck Serono, Novartis and Sanofi Aventis. She is a member of the steering committee of a trial sponsored by Merck Serono and is the Italian coordinator of a Biogen-Dompe study. She has also received travel and research grants from the Associazione Italiana Sclerosi Multipla and is a consultant of 'Fondazione Cesare Serono'. GIz has received honoraria for consultation from Biogen Idec, Merck Serono, Teva, Bayer, Novartis and Sanofi Aventis. FG is a Novartis advisory board member and receives Speakers Bureau from Teva and research grants from Genzyme, Novartis, BiogenIdec, Teva, ONO, UBC and EMD Serono. PD reports participating in advisory boards for TEVA, EMD Serono, Biogen Idec, Novartis and Bayer Schering. He also receives research grants from Biogen Idec, CIHR and the MS Society of Canada. MG reports participating in advisory boards for Teva Neuroscience and Biogen Idec. He has received travel grants from Biogen Idec and EMD Serono as well as honoraria for speaking engagements from Teva Neurosciences, Biogen Idec, EMD Serono and Novartis Pharma. PG has received research grants from Sanofi-Avantis and Biogen-Idec. PG has also received honoraria for advisory councils and teaching programs with Novartis Pharma, Teva Neuroscience, EMD Serono, Biogen Idec and Bayer. CO-G has received honoraria as consultant in scientific advisory boards by Biogen-Idec, Bayer-Schering, Merck-Serono, Teva and Novartis and has also participated in clinical trials and other research projects promoted by Biogen-Idec, GSK, Teva and Novartis. RH has received honoraria for consultancy for Biogen Idec, reports participating in an advisory board for Merck Serono and has received grants from Biogen Idec and Merck Serono. RB has received research grants from Bayer-Schering, Biogen Dompe, Novartis, Sanofi Aventis and Merck Serono; honoraria for speaking from Bayer-Schering, Sanofi Aventis and Merck Serono; grants to cover travel expenses from Bayer-Schering, Biogen Dompe, Sanofi Aventis, Merck Serono and Novartis. MER has received payment for lectures from Serono Symposia International. JL-S institution receives non-directed funding as well as honoraria for presentations and membership on advisory boards from Sanofi Aventis, Biogen Idec, Bayer Health Care, Merck Serono and Novartis Australia. VvP serves on an advisory board for Biogen Idec. He has received travel grants from Biogen Idec, Bayer Schering, Sanofi Aventis, Merck Serono and Novartis Pharma and speaking honoraria from Biogen Idec. MF received conference travel support from Merck Serono. FV has received honoraria as a member of an advisory board for Merck Serono. MB has received research support and/or honoraria from Bayer Schering, Biogen Idec, Merck Serono, Novartis Pharma, Sanofi Aventis and Teva. MS reports participating in advisory boards for Sanofi Aventis, Merck Serono, Biogen Idec, Novartis Pharma and Bayer Schering. JH receives honoraria from Teva, Bayer, Merck Serono and Biogen Idec.IK has received grants from the National MS Societ and Bayer. NV receives honoraria from Novartis Pharma and conference travel support from Biogen Idec, Eisai, GSK, Novartis and Bayer Schering. FM has participated in MS clinical trials sponsored by EMD Serono and Bayer and has received honorarium from Teva and Bayer for consultancy, EMD Serono for organisation of a teaching course and Serono for speaking. He has also received conference support from Serono, Teva and Biogen. SHa has received an unrestricted educational grant and travel grants from Merck Serono. OG has received unrestricted educational grants from Merck Serono and Biogen Idec. HB has served on scientific advisory boards for Biogen Idec, Novartis and Sanofi-Aventis and has received conference travel support from Novartis, Biogen Idec and Sanofi Aventis. He serves on steering committees for trials conducted by Merck Serono, Biogen Idec and Novartis. HB has received research support from Merck Serono, Novartis and Biogen Idec in his capacity as honorary chair of the MSBase Foundation. He is on the editorial board of Multiple Sclerosis International. He is the recipient of a National Health and Medical Research Council (NHMRC) Career Development Award (628856), NHMRC Project Grants (566513, 628799, 1009757), NHMRC Centre of Excellence Award (1001216), an Australian Research Council Linkage Grant (LP110100473) RG and a National MS Society (USA) Project Grant (RG3850A3/1). TS, CB, GG, GIu, TP-B, VS, VJ, GM and FK report no disclosures.