Book Chapter

Metabolomics - The Combination of Analytical Biochemistry, Biology, and Informatics

U Roessner, A Nahid, B Chapman, A Hunter, M Bellgard

COMPREHENSIVE BIOTECHNOLOGY, VOL 1: SCIENTIFIC FUNDAMENTALS OF BIOTECHNOLOGY, 2ND EDITION | ELSEVIER SCIENCE BV | Published : 2011

Abstract

The combination of analytical biochemistry to measure the metabolic complement with sophisticated informatics, bioinformatics, and statistics makes up the newest of the 'omics fields called metabolomics. Metabolites are characterized by a diverse chemistry and therefore require the application of numerous analytical approaches for their extraction, separation, detection, and quantification. In the past decade, the technologies have improved substantially allowing the analysis of thousands of compounds simultaneously. However, this has led to the current bottleneck in metabolomics that is how to extract information from raw data of many different analytical platforms and the subsequent approp..

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University of Melbourne Researchers