Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
Marilyn B Renfree, Anthony T Papenfuss, Janine E Deakin, James Lindsay, Thomas Heider, Katherine Belov, Willem Rens, Paul D Waters, Elizabeth A Pharo, Geoff Shaw, Emily Swwong, Christophe M Lefevre, Kevin R Nicholas, Yoko Kuroki, Matthew J Wakefield, Kyall R Zenger, Chenwei Wang, Malcolm Ferguson-Smith, Frank W Nicholas, Danielle Hickford Show all
GENOME BIOLOGY | BMC | Published : 2011
BACKGROUND: We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hopping mammals that symbolize Australia to be sequenced. The tammar has many unusual biological characteristics, including the longest period of embryonic diapause of any mammal, extremely synchronized seasonal breeding and prolonged and sophisticated lactation within a well-defined pouch. Like other marsupials, it gives birth to highly altricial young, and has a small number of very large chromosomes, making it a valuable model for genomics, reproduction and development. RESULTS: The genome has been sequenced to 2 × coverage..View full abstract
Awarded by National Human Genome Research Institute of the National Institutes of Health
Awarded by NATIONAL HUMAN GENOME RESEARCH INSTITUTE
This study was supported by the State Government of Victoria, the National Human Genome Research Institute of the National Institutes of Health (grant number U54-HG003273), the Australian Genome Research Facility (AGRF), the Jack Brockhoff Foundation, Applied Biosystems, the Australian Research Council Centre of Excellence in Kangaroo Genomics, the National Science Foundation and the Center for Applied Genetics and Technology at University of Connecticut (UConn). This work was supported in part by KAKENHI (Grant-in-Aid for Scientific Research) on Priority Areas 'Comparative Genomics' from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and by the Director's Special Grant from RIKEN-GSC. The Baylor College of Medicine Human genome Sequencing Center (HGSC) acknowledges the following production staff of the HGSC: Jennifer Hume, John Lopez, Kashif Hirani, Lingling Pu, Marvin D Dao, Mimi N Chandrabose, Ngoc B Nguyen, Ramatu A Gabisi, Rita A Wright, Sandra Hines, Yih-Shin Liu, Ugonna Anosike, Tony Attaway, Dilrukshi Bandaranaike, Ashton Bell, Blake Beltran, Carla Bickham, Temika Caleb, Kelvin Carter, Joseph Chacko, Alejandra Chavez, Hau-Seng Chu, Raynard Cockrell, Mary Louise Davila, Latarsha DavyCarroll, Shawn Denson, Victor Ebong, Veronica Espinosa, Sonia Fernandez, Pushpa Fernando, Nicole Flagg, Jason Ganer, Ricardo Garcia III, Toni Garner, Tiffany Garrett, Brandy Harbes, Ebere Hawkins, Barbara Hollins, Bennie Johnson, Johann Kalu, Haika Kisamo, Michael Lago, Liza Lago, Chuan-Yar Lai, Thanh-Kim Le, Fitzherbert Legall III, Semethia Lemon, Renita Madu, Kevin Malloy, Evangelina Martinez, Christian Mercado, Iracema Mercado, Mala Munidasa, Phong Nguyen, Ogechi Nwaokelemeh, Melissa Obregon, Chibueze Onwere, Andrea Parra, Agapito Perez, Yolanda Perez, Christopher Pham, Eltrick Primus, Maria Puazo, Juana Quiroz, Eric Rachlin, Marcos Ruiz, Brian Schneider, Denard Simmons, Ida Sisson, Rosenie Thelus, Nicole Thomas, Rachel Thorn, Reshaunda Thornton, Zulma Trejos, Kamran Usmani, Davian Walker, Keqing Wang, Suzhen Wang, Courtney White, Aneisa Williams and Jerrell Woodworth.