Congenital hepatic fibrosis with polycystic kidney disease in a Persian cat from New Zealand

Abstract

This report describes atypical clinical features of a cat with feline polycystic kidney disease. An 18-month old Persian cat presented to Massey University Veterinary Teaching Hospital with a three week history of failure to gain weight, ptyalism, vomiting, diarrhoea and lethargy. Mental obtundation and firm hepatomegaly were noted during physical examination. A low serum urea concentration and increased alkaline phosphatase concentration were noted. Pre and post prandial bile acid concentration was elevated above the reference interval. Abdominal ultrasound examination demonstrated diffuse moderate hepatomegaly with a homogenous coarse hyperechoic appearance to the parenchyma, numerous smal..