Journal article
Minimization of Human Relaxin-3 Leading to High-Affinity Analogues with Increased Selectivity for Relaxin-Family Peptide 3 Receptor (RXFP3) over RXFP1
Fazel Shabanpoor, Mohammad Alchter Hossain, Philip J Ryan, Alessia Belgi, Sharon Layfield, Martina Kocan, Suode Zhang, Chrishan S Samuel, Andrew L Gundlach, Ross AD Bathgate, Frances Separovic, John D Wade
Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2012
DOI: 10.1021/jm201505p
Grants
Awarded by NHMRC (Australia)
Funding Acknowledgements
This research was funded by NHMRC (Australia) project grants 350284, 508995 to J.D.W. and R.A.D.B., and 509246 to A.L.G. We are grateful to Tania Ferraro for assistance with biochemical assays and to Dr. Tony Hughes (Department of Pharmacology, The University of Melbourne) for valuable advice. During these studies, M.A.H. was the recipient of a Reid Trust Fellowship, and P.J.R was the recipient of a Commonwealth Australian Postgraduate Award and a Dowd Foundation Scholarship. J.D.W., R.A.D.B., and A.L.G. are NHMRC Research Fellows, and C.S.S. is an NHF Research Fellow. Studies at the FNI were supported by the Victorian Government's Operational Infrastructure Support Program.