Evidence for increased internal noise in migraineurs for contrast and shape processing
Kathryn E Webster, J Edwin Dickinson, Josephine Battista, Allison M McKendrick, David R Badcock
Cephalalgia: an international journal of headache | SAGE PUBLICATIONS LTD | Published : 2012
AIM: Increased contrast-level dependent internal noise has been reported in migraine. This study aimed to investigate whether a general increase in internal noise impacted on other tasks thought to assess functioning in cortical area V1 and was evident in global contour coding (V4). METHODS: Eleven migraineurs (six with aura) and 12 headache-free controls completed three psychophysical tasks: (i) contrast detection, (ii) discrimination of the angle of a spiral path and (iii) detection of deformation from circularity. Internal noise estimates were obtained using an N-pass method that compared responses to repeated presentations of identical stimuli. Internal noise results in inconsistent resp..View full abstract
Awarded by NHMRC
This research was supported by NHMRC Project grant #509208 (to authors AMM and DRB).