Journal article
Online adaptive radiotherapy for muscle-invasive bladder cancer: Results of a pilot study
F Foroudi, J Wong, T Kron, A Rolfo, A Haworth, P Roxby, J Thomas, A Herschtal, D Pham, S Williams, KH Tai, G Duchesne
International Journal of Radiation Oncology Biology Physics | Published : 2011
Abstract
Purpose: To determine the advantages and disadvantages of daily online adaptive image-guided radiotherapy (RT) compared with conventional RT for muscle-invasive bladder cancer. Methods and Materials: Twenty-seven patients with T2-T4 transitional cell carcinoma of the bladder were treated with daily online adaptive image-guided RT using cone-beam computed tomography (CBCT). From day 1 daily soft tissue-based isocenter positioning was performed using CBCT images acquired before treatment. Using a composite of the initial planning CT and the first five daily CBCT scans, small, medium, and large adaptive plans were created. Each of these adaptive plans used a 0.5-cm clinical target volume (CTV) ..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
Funded in part by Victorian Cancer Agency Pilot Study Funding CT 07 006 and a National Health and Medical Research Council Project Grant. The Peter MacCallum Cancer Centre has a Research Collaborative Agreement with Varian Medical Systems.