Neurochemical classification and projection targets of CART peptide immunoreactive neurons in sensory and parasympathetic ganglia of the head

JJ Ivanusic; KE Goulding; MMK Kwok; EA Jennings

Journal article

Neurochemical classification and projection targets of CART peptide immunoreactive neurons in sensory and parasympathetic ganglia of the head

JJ Ivanusic, KE Goulding, MMK Kwok, EA Jennings

Neuropeptides | Published : 2012

DOI: 10.1016/j.npep.2011.09.002

Abstract

The aims of the present study were to determine if there is neuronal Cocaine and amphetamine regulated transcripts (CART) peptide expression (CART+) in parasympathetic (sphenopalatine (SPG); otic (OG)) and sensory (trigeminal (TG)) ganglia of the head and to examine the neurochemical phenotype (calcitonin gene-related peptide (CGRP), neurofilament 200 (NF200), isolectin B4 (IB4) binding, vasoactive intestinal peptide (VIP), neuropeptide Y (NPY) and enkephalin (ENK) immunoreactivity) and projection targets (lacrimal gland (LG), parotid gland (PG), nasal mucosa (NM), temporomandibular joint (TMJ), middle cerebral artery (MCA) and middle meningeal artery (MMA)) of CART expressing neurons in the..

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University of Melbourne Researchers

Jason Ivanusic Author

Grants

Funding Acknowledgements

This study was supported by funding from the Australian National Health and Medical Research Council and the Australian Brain Foundation. The authors thank A/Prof. Colin Anderson for advice and assistance in the design and interpretation of aspects of this study.