Journal article

Histochemical and morphometric characterization of broncho-pneumonia in calves caused by infection with Mycoplasma bovis

NK Wawegama, A Kanci, MS Marenda, PD Mansell, GF Browning, PF Markham

Veterinary Microbiology | Elsevier | Published : 2012


The aim of this study was to identify morphometric histological features of pneumonia caused by Mycoplasma bovis in calves. Eight three-month-old calves were infected with M. bovis and samples of their lung tissue, three weeks after exposure, compared to samples from four uninfected calves. In the uninfected animals the goblet cells were clustered in the crypt area of the epithelial folds, while in the infected calves they had migrated towards the tips of the folds and were distributed evenly throughout the folds. In infected lung tissue there was goblet cell hyperplasia and metaplasia in the bronchioles and an increased epithelial height. Goblet cell mucin in uninfected calves was acidic, b..

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Funding Acknowledgements

N.K. Wawegama was supported by the Melbourne International Fee Remission and Melbourne International Research Scholarships. The authors like to thank Ms. F. Doherty for her assistance in preparing and staining the histological sections and Ms. C. Colson for care of the calves during the experiment.