Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer
EJH Wee, K Peters, SS Nair, T Hulf, S Stein, S Wagner, P Bailey, SY Lee, WJ Qu, B Brewster, JD French, A Dobrovic, GD Francis, SJ Clark, MA Brown
Oncogene | NATURE PUBLISHING GROUP | Published : 2012
This project was funded by grants from the National Breast Cancer Foundation (NBCF), Cancer Australia and National Health and Medical Research Council (NHMRC). We are grateful to Dr Maja Klug for generously providing the CpG-Less reporter plasmid.