Journal article

The Wnt Receptor Ryk Plays a Role in Mammalian Planar Cell Polarity Signaling

Maria L Macheda, Willy W Sun, Kumudhini Kugathasan, Benjamin M Hogan, Neil I Bower, Michael M Halford, You Fang Zhang, Bonnie E Jacques, Graham J Lieschke, Alain Dabdoub, Steven A Stacker

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2012

Grants

Awarded by National Institutes of Health


Awarded by National Institutes of Health NS/NINDS HHS


Awarded by NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE


Awarded by NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS


Funding Acknowledgements

This work was supported in part by a program grant (to S. A. S.) from the National Health and Medical Research Council of Australia and Grant R01DC011104 (to A. D.) from the National Institutes of Health.Supported by a Senior Research Fellowship from the National Health and Medical Research Council of Australia and a Pfizer Australia Fellowship. To whom correspondence should be addressed: Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St., Melbourne, Victoria 8006, Australia. Tel.: 61-3-9656-5263; Fax: 61-3-9656-1411; E-mail: steven.stacker@petermac.org.We thank R. Moon for the super TOP-FLASH and super FOP-FLASH plasmids; A. McMahon for the Wnt3a and Wnt11 plasmids; R. Habas for the pGEX-RBD plasmid; Y. Zou for the anti-Ryk antibodies; S. Jane for providing the Vangl2<SUP>Lp</SUP> mice; A. Naughton and staff at the Biological Resource Facility at the Ludwig Institute for Cancer Research, Melbourne, Australia, for assistance with mouse experiments; S. Cody for assistance with imaging; S. Paquet-Fifield for assistance with photography; and M. Achen for critical reading of the manuscript. Fluorescent images were generated at the University of California, San Diego, Neuroscience Microscopy Shared Facility supported by National Institutes of Health NS/NINDS HHS Grant P30-NS047101.